VEGFA antibody
Catalogue Number: GTX74091-GTX
GTX74091 Image
GTX74091 Image
GTX74091 Image
GTX74091 Image
GTX74091 Image
IHC-P analysis of mouse kidney tissue using GTX74091 VEGFA antibody.
GTX74091 Image
IHC-P analysis of mouse kidney tissue using GTX74091 VEGFA antibody.
GTX74091 Image
IHC-P analysis of mouse kidney tissue using GTX74091 VEGFA antibody.
GTX74091 Image
IHC-P analysis of mouse kidney tissue using GTX74091 VEGFA antibody.
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 25 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | vascular endothelial growth factor A , Vegf , Vpf |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant mouse VEGF |
| Application: | ELISA, ICC, IF, IHC-P, WB, FA |
Description
Description: This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.[provided by RefSeq, Nov 2015]
Additional Text
Gene Name
VEGFA
Uniprot ID
Q00731
Gene ID
22339
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
25
Concentration
1 mg/ml
Application Notes
WB: 0.1-0.2µg/ml. ICC/IF: 2.5µg/ml. IHC-P: 2.5µg/ml. ELISA: 0.5µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX74091 Datasheet
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DELIVERY
we offer free delivery to UK universities and non profit organisations