IL13 antibody

Catalogue Number: GTX74166-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:16
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:interleukin 13 , IL-13 , P600
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant human IL-13
Application: ELISA, WB, FA

Description

Description: This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

IL13

Uniprot ID

P35225

Gene ID

3596

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

16

Concentration

1 mg/ml

Application Notes

WB: 0.1-0.2µg/ml. ELISA: 0.5µg/ml (direct ELISA). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.