IL15 antibody
Catalogue Number: GTX74169-GTX
GTX74169 Image
GTX74169 Image
GTX74169 Image
GTX74169 Image
IHC-P analysis of normal human placenta tissue using GTX74169 IL15 antibody.
GTX74169 Image
IHC-P analysis of normal human placenta tissue using GTX74169 IL15 antibody.
GTX74169 Image
IHC-P analysis of normal human placenta tissue using GTX74169 IL15 antibody.
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 18 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | interleukin 15 , IL-15 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant human IL-15 |
| Application: | ELISA, IHC-P, IP, WB, NT, Inh |
Description
Description: The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
Additional Text
Uniprot ID
P40933
Gene ID
3600
Gene Name
IL15
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
18
Concentration
1 mg/ml
Application Notes
WB: 0.1-0.2µg/ml. ELISA: 0.5µg/ml. Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX74169 Datasheet
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