CSK antibody
Catalogue Number: GTX74502-GTX
GTX74502 Image
GTX74502 Image
GTX74502 Image
GTX74502 Image
IHC-P analysis of human colon tissue using GTX74502 CSK antibody. Antigen retrieval using citrate buffer at pH6.0.
GTX74502 Image
WB analysis of Jurkat cell lysate using GTX74502 CSK antibody at 0.5µg/ml
GTX74502 Image
WB analysis of mouse spleen tissue lysate using GTX74502 CSK antibody at 1 µg/ml
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 51 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | C-terminal Src kinase |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide sequence EQLEHIKTHELHL corresponding to the C-terminal region of CSK (NP_004374.1). |
| Application: | ELISA, IHC-P, WB |
Description
Description: The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Additional Text
Gene ID
1445
Gene Name
CSK
Uniprot ID
P41240
Concentration
0.5 mg/ml
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
51
Application Notes
WB: 0.5-2µg/ml. IHC-P: 0.1-0.3µg/ml. ELISA: >1/32,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX74502 Datasheet
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