CD62L antibody [FMC46] (PE)

Catalogue Number: GTX74632-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:42
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:selectin L , CD62L , LAM1 , LECAM1 , LEU8 , LNHR , LSEL , LYAM1 , PLNHR , TQ1
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: FMC46
Isotype: IgG2b
Immunogen: PHA stimulated lymphoblasts.
Application: FC

Description

Description: This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]

Additional Text

Gene Name

SELL

Uniprot ID

P14151

Gene ID

6402

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: Neat. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.