CD86 antibody [BU63] (PE)

Catalogue Number: GTX74652-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:38
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD86 molecule , B7-2 , B7.2 , B70 , CD28LG2 , LAB72
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: BU63
Isotype: IgG1
Immunogen: Human peripheral blood lymphocytes.
Application: FC

Description

Description: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]

Additional Text

Gene Name

CD86

Gene ID

942

Uniprot ID

P42081

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: Neat-1/10. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.