IL2 Receptor alpha antibody [PC61.5.3.] (PE)

Catalogue Number: GTX74803-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:31
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:interleukin 2 receptor subunit alpha , CD25 , IDDM10 , IL2R , IMD41 , TCGFR , p55
Shipping Condition:Blue Ice
Unit(s): 500 ul
Host name: Rat
Clone: PC61.5.3.
Isotype: IgG1
Immunogen: B6.1 CTL cell line
Application: FC

Description

Description: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]

Additional Text

Gene Name

IL2RA

Gene ID

3559

Uniprot ID

P01589

Concentration

0.1 mg/ml

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

For FACS: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.