CD11c antibody [N418] (FITC)
Catalogue Number: GTX74938-GTX
GTX74938 Image
GTX74938 Image
FACS analysis of C57Bl/6 splenocytes stained APC anti-mouse MHC Class II antibody, followed by staining with GTX74938 CD11c antibody [N418] (FITC). Right panel : Co-stained with APC anti-mouse MHC Class II antibody and GTX74938 Left panel : Co-stained with APC anti-mouse MHC Class II antibody and FITC Armenian hamster IgG isotype control Antibody amount : 0.25 µg
| Manufacturer: | GeneTex |
| Preservative: | 0.09% sodium azide |
| Molecular Weight: | 129 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | integrin alpha X , AI449405 , Cd11c , Cr4 , N418 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Armenian Hamster |
| Clone: | N418 |
| Isotype: | IgG2 |
| Immunogen: | Mouse spleen dendritic cells. |
| Application: | FC |
Additional Text
Gene Name
ITGAX
Concentration
0.5 mg/ml
Uniprot ID
Q9QXH4
Purification
Affinity Purified
Gene ID
16411
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Short Description
The N418 antibody reacts with mouse CD11c, also known as integrin αalpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin αreceptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrin αs are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin αreceptors consist of distinct combinations of integrin αchains which are differentially expressed. integrin αalpha X (CD11c) assembles with integrin αbeta-2 (CD18) into a receptor complex known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.
GTX74938 Datasheet
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