Integrin alpha 6 antibody [450-30A] (FITC)

Catalogue Number: GTX75045-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:127
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:integrin subunit alpha 6 , CD49f , ITGA6B , VLA-6
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 450-30A
Isotype: IgG1
Immunogen: integrin a6b4 purified from A431 cells
Application: FC

Description

Description: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Additional Text

Gene Name

ITGA6

Gene ID

3655

Uniprot ID

P23229

Concentration

0.1 mg/ml

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. Protect from light.

Application Notes

FCM: Neat. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.