ICAM1 / CD54 antibody [15.2] (PE)

Catalogue Number: GTX75219-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:58
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:intercellular adhesion molecule 1 , BB2 , CD54 , P3.58
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: 15.2
Isotype: IgG1
Immunogen: Human monocytes
Application: FC

Description

Description: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

ICAM1

Gene ID

3383

Uniprot ID

P05362

Concentration

0.1 mg/ml

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Short Description

The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin αprotein family, LFA-1 (CD11a).

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 0.5 µg (5 µl) for 10⁵-10⁸ cells in 100 µl sample per test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.