LRP1 antibody [A2Mr alpha-2] (PE)

Catalogue Number: GTX75659-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	505
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	LDL receptor related protein 1 , A2MR , APOER , APR , CD91 , IGFBP-3R , IGFBP3R , IGFBP3R1 , KPA , LRP , LRP1A , TGFBR5
Shipping Condition:	Blue Ice
Unit(s):	50 tests
Host name:	Mouse
Clone:	A2Mr alpha-2
Isotype:	IgG1
Immunogen:	Purified LRP1
Application:	FC

Overview
Datasheets

Description

Description: This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]

Additional Text

Gene ID

4035

Uniprot ID

Q07954

Gene Name

LRP1

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: Neat. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX75659 Datasheet

Price

£312.00

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Quantity
Unit Size

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