CD177 antibody [MEM-166] (FITC)

Catalogue Number: GTX75710-GTX

Manufacturer:	GeneTex
Preservative:	15 mM Sodium azide
Molecular Weight:	46
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD177 , CD177 molecule , HNA2A , HNA2a , NB1 , NB1 GP , PRV1
Shipping Condition:	Blue Ice
Unit(s):	100 tests
Host name:	Mouse
Clone:	MEM-166
Isotype:	IgG1
Immunogen:	Human granulocytes
Application:	FC

Overview
Datasheets

Description

Description: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]

Additional Text

Gene ID

57126

Gene Name

CD177

Uniprot ID

Q8N6Q3

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 20 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX75710 Datasheet

Price

£284.00

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