CD11c antibody [BU15] (FITC)

Catalogue Number: GTX75794-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:128
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD11C , ITGAX , SLEB6 , integrin subunit alpha X , CD11c , Integrin alpha X
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: BU15
Isotype: IgG1
Immunogen: Dendritic cells of synovial fluid
Application: FC

Description

Description: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Additional Text

Gene Name

ITGAX

Gene ID

3687

Uniprot ID

P20702

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 20 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.