HLA-A2 antibody [BB7.2] (Low endotoxin, azide free)

Catalogue Number: GTX75806-GTX

Manufacturer:	GeneTex
Preservative:	azide free\|no preservative\|No preservative
Molecular Weight:	41
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	Major Histocompatibility Complex, Class I, A , Hlaa , Hla-A
Shipping Condition:	Blue Ice
Unit(s):	500 ug
Host name:	Mouse
Clone:	BB7.2
Isotype:	IgG2b
Immunogen:	Papain solubilised HLA-A2
Application:	FC, ICC, IF, IP, IHC-Fr, NT, Blk, Inh

Overview
Datasheets

Description

Description: HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

3105

Gene Name

HLA-A

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

FCM: 10µg/ml. Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX75806 Datasheet

GTX75806 Reference

Price

£765.00

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Quantity
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