CD46 antibody [MEM-258] (FITC)

Catalogue Number: GTX75834-GTX

Manufacturer:	GeneTex
Preservative:	15 mM Sodium azide
Molecular Weight:	44
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	AHUS2 , CD46 , CD46 molecule , MCP , MIC10 , TLX , TRA2.10
Shipping Condition:	Blue Ice
Unit(s):	100 tests
Host name:	Mouse
Clone:	MEM-258
Isotype:	IgG1
Immunogen:	HPB-ALL human T cell line
Application:	FC

Overview
Datasheets

Description

Description: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]

Additional Text

Gene Name

CD46

Gene ID

4179

Uniprot ID

P15529

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 20 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX75834 Datasheet

Price

£284.00

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Quantity
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