Granzyme B antibody [GB10] (Biotin)

Catalogue Number: GTX75842-GTX

Manufacturer:GeneTex
Preservative:0.001% Thimerosal|0.001% Thimerosal
Molecular Weight:28
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:granzyme B , C11 , CCPI , CGL-1 , CGL1 , CSP-B , CSPB , CTLA1 , CTSGL1 , HLP , SECT
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Mouse
Clone: GB10
Isotype: IgG1
Immunogen: Purified human Granzyme B.
Application: ELISA

Description

Description: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

Additional Text

Gene Name

GZMB

Gene ID

3002

Concentration

0.5 mg/ml

Purification

Protein A purified

Uniprot ID

P10144

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

ELISA: 1µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.