IL2 Receptor alpha antibody [MEM-181] (PE-Cy7)

Catalogue Number: GTX75869-10-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:31
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD25 , IDDM10 , IL2R , IL2RA , IMD41 , TCGFR , interleukin 2 receptor subunit alpha , p55 , IL2-R alpha
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: MEM-181
Isotype: IgG1
Immunogen: PHA-activated peripheral blood leucocytes
Application: FC

Description

Description: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]

Additional Text

Gene Name

IL2RA

Gene ID

3559

Uniprot ID

P01589

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.