CD11b antibody [ICRF44] (Azide free)

Catalogue Number: GTX76296-GTX

Manufacturer:	GeneTex
Preservative:	Azide free\|no preservative\|No preservative
Molecular Weight:	127
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	integrin subunit alpha M , CD11B , CR3A , MAC-1 , MAC1A , MO1A , SLEB6
Shipping Condition:	Blue Ice
Unit(s):	200 ug
Host name:	Mouse
Clone:	ICRF44
Isotype:	IgG1
Immunogen:	Rheumatoid synovial cells and human monocytes.
Application:	FC, IP, IHC-Fr, FA

Overview
Datasheets

Description

Description: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Additional Text

Gene Name

ITGAM

Gene ID

3684

Uniprot ID

P11215

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

IHC-Fr: 1/50-1/500. FCM: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX76296 Datasheet

Price

£499.00

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