CD43 antibody [DFT-1] (FITC)

Catalogue Number: GTX76309-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:40
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:sialophorin , CD43 , GALGP , GPL115 , LSN
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Mouse
Clone: DFT-1
Isotype: IgG1
Immunogen: KG-1 cells.
Application: FC

Description

Description: This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]

Additional Text

Gene Name

SPN

Concentration

0.1 mg/ml

Purification

Protein G purified

Gene ID

6693

Uniprot ID

P16150

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. Protect from light.

Application Notes

FCM: Neat. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.