C3 / C3a antibody

Catalogue Number: GTX78199-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:187
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:complement C3 , AHUS5 , ARMD9 , ASP , C3a , C3b , CPAMD1 , HEL-S-62p
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Mouse C3 alpha peptide aa 678-692
Application: ELISA, WB

Description

Description: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]

Additional Text

Gene Name

C3

Uniprot ID

P01024

Gene ID

718

Purification

Affinity Purified

Molecular Weight

187

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

This product can be used at 1:2,000 to 1:10,000 for both ELISA and immunoblot testing. User needs to try out the titrations for optimization in assay.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.