Active Ghrelin antibody

Catalogue Number: GTX78202-GTX

Manufacturer:	GeneTex
Preservative:	0.02% Sodium azide\|0.02% Sodium azide
Molecular Weight:	13
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	ghrelin and obestatin prepropeptide , MTLRP
Shipping Condition:	Blue Ice
Unit(s):	200 ug
Host name:	Chicken
Clone:
Isotype:	IgY
Immunogen:	GSS(n_octanoyl)FLSPEH
Application:	ELISA

Overview
Datasheets

Description

Description: This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]

Additional Text

Gene ID

51738

Gene Name

GHRL

Uniprot ID

Q9UBU3

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

For ELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX78202 Datasheet

Price

£374.00

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Quantity
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