CD11a antibody [MEM-25] (Biotin)

Catalogue Number: GTX78266-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:129
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD11A , ITGAL , LFA1 , LFA1A , integrin subunit alpha L , CD11a , LFA-1
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: MEM-25
Isotype: IgG1
Immunogen: Leukocytes from a pacient suffering from a LGL-type leukaemia.
Application: FC, IP

Description

Description: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

Itgal

Gene ID

3683

Uniprot ID

P20701

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.