CD45 antibody [MEM-28] (Biotin)

Catalogue Number: GTX78292-GTX

Manufacturer:	GeneTex
Preservative:	15 mM Sodium azide
Molecular Weight:	147
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	protein tyrosine phosphatase receptor type C , B220 , CD45 , CD45R , GP180 , L-CA , LCA , LY5 , T200
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	MEM-28
Isotype:	IgG1
Immunogen:	Human thymocytes and T lymphocytes.
Application:	FC, ICC, IF, IHC-P, IP, WB

Overview
Datasheets

Description

Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

Additional Text

Gene Name

PTPRC

Gene ID

5788

Molecular Weight

147

Uniprot ID

P08575

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.

GTX78292 Datasheet

Price

£374.00

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