Catalogue Number: GTX78340-GTX
Manufacturer: | GeneTex |
Preservative: | 15mM Sodium azide |
Physical state: | Liquid |
Type: | Monoclonal Primary Antibody - Conjugated |
Alias: | END , ENG , HHT1 , ORW1 , endoglin , CD105 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 tests |
Host name: | Mouse |
Clone: | MEM-226 |
Isotype: | IgG2a |
Immunogen: | Recombinant Vaccinia virus containing the human CD105 cDNA. |
Application: | FACS |
Description: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
ENG
2022
71
P17813, Q5T9B9
Monoclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption