CD105 antibody [MEM-226] (Dyomics 6477)

Catalogue Number: GTX78340-GTX

Manufacturer:GeneTex
Preservative:15mM Sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:END , ENG , HHT1 , ORW1 , endoglin , CD105
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: MEM-226
Isotype: IgG2a
Immunogen: Recombinant Vaccinia virus containing the human CD105 cDNA.
Application: FACS

Description

Description: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Additional Text

Gene Name

ENG

Gene ID

2022

Molecular Weight

71

Uniprot ID

P17813, Q5T9B9

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption