uPA antibody
Catalogue Number: GTX79594-GTX
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 49 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | ATF,BDPLT5,PLAU,QPD,UPA,URK,plasminogen activator, urokinase,uPA,Urokinase |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Sheep |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant full length wild-type human protein (Glycosylated). |
| Application: | ELISA, WB |
Description
Description: This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Additional Text
Concentration
10 mg/mL
Uniprot ID
P00749
Gene ID
5328
Gene Name
PLAU
Purification
Protein G purified
Molecular Weight
49
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX79594 Datasheet
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