tPA antibody (FITC)

Catalogue Number: GTX79612-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:63
Physical state:Liquid
Type:Polyclonal Primary Antibody - Conjugated
Alias:PLAT,TPA,plasminogen activator, tissue type,tPA,TPA Tissue Plasminogen Activator
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Sheep
Clone:
Isotype: IgG
Immunogen: Recombinant full length wild-type human protein (Glycosylated).
Application: ELISA

Description

Description: This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Additional Text

Concentration

10 mg/mL

Uniprot ID

P00750

Gene ID

5327

Gene Name

PLAT

Purification

Protein G purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. Protect from light.