Prorenin antibody [4B5-E3] (Biotin)

Catalogue Number: GTX79681-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Molecular Weight:	45
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	HNFJ2,REN,renin,Renin,Prorenin
Shipping Condition:	Blue Ice
Unit(s):	50 ug
Host name:	Mouse
Clone:	4B5-E3
Isotype:	IgG2b
Immunogen:	Recombinant full length wild-type human protein (Glycosylated).
Application:	ELISA, WB, NT, Inh

Overview
Datasheets

Description

Description: Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

REN

Gene ID

5972

Molecular Weight

Uniprot ID

P00797

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX79681 Datasheet

Price

£410.00

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