Factor X antibody (HRP)

Catalogue Number: GTX79772-GTX

Manufacturer:	GeneTex
Preservative:	0.01% Thimerosal\|0.01% Thimerosal
Molecular Weight:	55
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Conjugated
Alias:	coagulation factor X , FX , FXA
Shipping Condition:	Blue Ice
Unit(s):	1 mg
Host name:	Sheep
Clone:
Isotype:	IgG
Immunogen:
Application:	ELISA

Overview
Datasheets

Description

Description: This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]

Additional Text

Concentration

2 mg/ml

Gene ID

2159

Gene Name

F10

Uniprot ID

P00742

Purification

Protein G purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

Not yet tested in other applications. Optimal dilutions should be determined experimentally by the researcher.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX79772 Datasheet

Price

£410.00

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Quantity
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