Factor IX antibody

Catalogue Number: GTX79808-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:52
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:F9,F9 p22,FIX,HEMB,P19,PTC,THPH8,coagulation factor IX,Factor IX
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Sheep
Clone:
Isotype: IgG
Immunogen: Full length native protein (purified) (Human).
Application: ELISA, WB

Description

Description: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015]

Additional Text

Concentration

10 mg/mL

Gene Name

F9

Uniprot ID

P00740

Gene ID

2158

Purification

Protein G purified

Molecular Weight

52

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.