CD3 epsilon antibody [UCHT1] (PerCP)

Catalogue Number: GTX79855-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:23
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD3E , CD3e molecule , IMD18 , T3E , TCRE , CD3 epsilon
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: UCHT1
Isotype: IgG1
Immunogen: human thymocytes followed by Sezary T cells
Application: FC

Description

Description: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

CD3E

Gene ID

916

Uniprot ID

P07766

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 10 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.