CD3 antibody [OKT3]

Catalogue Number: GTX79906-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD3d molecule , CD3e molecule , CD3g molecule , CD3-DELTA , IMD19 , T3D , IMD18 , T3E , TCRE , CD3-GAMMA , IMD17 , T3G
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug
Host name: Mouse
Clone: OKT3
Isotype: IgG2a
Immunogen: Commercially sensitive information
Application: FC, IHC-P, IHC-Fr, Depl, Act

Additional Text

Concentration

0.5 mg/ml

Purification

Affinity Purified

Uniprot ID

P04234, P07766, P09693

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Gene ID

915; 916; 917

Gene Name

CD3D, CD3E, CD3G

Short Description

The OKT3 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.