HLA-E antibody [MEM-E/07] (Biotin)

Catalogue Number: GTX79922-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:40
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:HLA6.2 , HLAE , QA1 , major histocompatibility complex, class I, E , HLA-E
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: MEM-E/07
Isotype: IgG1
Immunogen: Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide.
Application: FC, IHC-P, IP

Description

Description: HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

HLA-E

Gene ID

3133

Uniprot ID

P13747

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.