CD44 antibody [MEM-85] (APC)

Catalogue Number: GTX79923-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:82
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD44 molecule (Indian blood group) , CDW44 , CSPG8 , ECMR-III , HCELL , HUTCH-I , IN , LHR , MC56 , MDU2 , MDU3 , MIC4 , Pgp1
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: MEM-85
Isotype: IgG2b
Immunogen: Leukocytes of a patient suffering from LGL Type Leukaemia.
Application: FC

Description

Description: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

CD44

Gene ID

960

Uniprot ID

P16070

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 10 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.