CD59 antibody [MEM-43] (APC)

Catalogue Number: GTX79946-GTX

Manufacturer:	GeneTex
Preservative:	15 mM Sodium azide
Molecular Weight:	14
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD59 , CD59 molecule , EJ16 , EJ30 , EL32 , G344 , HRF20 , MACIF , MACIP , MEM43 , MIC11 , MIN1 , MIN2 , MIN3 , MIRL , MSK21 , p1820 , CD59 molecule (CD59 blood group) , 1F5 , 16.3A5
Shipping Condition:	Blue Ice
Unit(s):	100 tests
Host name:	Mouse
Clone:	MEM-43
Isotype:	IgG2a
Immunogen:	Thymocytes and T lymphocytes
Application:	FC

Overview
Datasheets

Description

Description: This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

CD59

Gene ID

966

Uniprot ID

P13987

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 10 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX79946 Datasheet

Price

£303.00

-

Quantity
Unit Size

Find out about delivery