CD30 antibody [MEM-268] (APC)

Catalogue Number: GTX79954-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:64
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD30 , D1S166E , Ki1 , TNF receptor superfamily member 8 , TNFRSF8
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: MEM-268
Isotype: IgG
Immunogen: Expression vector containing CD30 cDNA (booster suspension of THP-1 cell line)
Application: FC

Description

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

TNFRSF8

Gene ID

943

Uniprot ID

P28908

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 10 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.