Catalogue Number: GTX80035-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.09% sodium azide |
| Molecular Weight: | 42 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | selectin, lymphocyte , AI528707 , CD62L , L-selectin , LECAM-1 , Lnhr , Ly-22 , Ly-m22 , Lyam-1 , Lyam1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | Mel-14 |
| Isotype: | IgG3a |
| Immunogen: | C3H/eb mouse B cell lymphoma 38C-13 |
| Application: | FC |
SELL
20343
0.5 mg/ml
Affinity Purified
P18337
Monoclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte "rolling" on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin αfamily of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.