CD44 antibody [IM7] (FITC)

Catalogue Number: GTX80087-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	82
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD44 molecule (Indian blood group) , CDW44 , CSPG8 , ECMR-III , HCELL , HUTCH-I , IN , LHR , MC56 , MDU2 , MDU3 , MIC4 , Pgp1
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Rat
Clone:	IM7
Isotype:	IgG3b
Immunogen:	Dexamethasone-induced cells of the SJL mouse spontaneous myeloid leukemia M1
Application:	FC

Overview
Datasheets

Description

Description: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

CD44

Gene ID

960

Concentration

0.5 mg/ml

Purification

Affinity Purified

Uniprot ID

P16070

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Short Description

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or "standard" form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

GTX80087 Datasheet

Price

£273.00

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Quantity
Unit Size

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