CD8 alpha antibody [53-6.7] (FITC)

Catalogue Number: GTX80264-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	27
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD8 antigen, alpha chain , BB154331 , Ly-2 , Ly-35 , Ly-B , Lyt-2
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Rat
Clone:	53-6.7
Isotype:	IgG2a
Immunogen:	Mouse spleen cells
Application:	FC

Overview
Datasheets

Additional Text

Gene Name

CD8A

Concentration

0.5 mg/ml

Gene ID

12525

Purification

Affinity Purified

Uniprot ID

P01731

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Short Description

The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

GTX80264 Datasheet

GTX80264 Reference

Price

£273.00

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