RPB1 antibody [4H8]

Catalogue Number: GTX80341-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:217
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:RNA polymerase II subunit A , POLR2 , POLRA , RPB1 , RPBh1 , RPO2 , RPOL2 , RpIILS , hRPB220 , hsRPB1
Shipping Condition:Blue Ice
Unit(s): 50 ul
Host name: Mouse
Clone: 4H8
Isotype: IgG1
Immunogen: 10 repeats of synthetic peptide YSPTSPS using chemically synthesized phospho-Ser 5 YSPTSpPS (Human). [UniProt# P24928]
Application: FC, ICC, IF, ChIP, WB

Description

Description: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

5430

Gene Name

POLR2A

Uniprot ID

P24928

Purification

Protein G purified

Molecular Weight

217

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

Optimal dilutions should be determined experimentally by the researcher.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.