ORC6 antibody [3A4]

Catalogue Number: GTX80357-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Molecular Weight:28
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:origin recognition complex subunit 6 , ORC6L
Shipping Condition:Blue Ice
Unit(s): 50 ul
Host name: Rat
Clone: 3A4
Isotype: IgG2a
Immunogen: ORC6 (hsORC)
Application: IP, ChIP, WB

Description

Description: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq, Oct 2010]

Additional Text

Gene Name

ORC6

Uniprot ID

Q9Y5N6

Purification

Protein G purified

Gene ID

23594

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

28

Concentration

1 mg/ml

Application Notes

Recommended Starting Dilutions:For WB: Use at 1:1000Optimal dilutions should be determined experimentally by the researcher.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.