hnRNP K antibody [3C2]

Catalogue Number: GTX80387-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Molecular Weight:51
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:heterogeneous nuclear ribonucleoprotein K , AUKS , CSBP , HNRPK , TUNP
Shipping Condition:Blue Ice
Unit(s): 50 ul
Host name: Mouse
Clone: 3C2
Isotype: IgG2b
Immunogen: Purified full length native human protein
Application: ELISA, FC, ICC, IF, IP, ChIP, WB

Description

Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

3190

Gene Name

HNRNPK

Uniprot ID

P61978

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

51

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1:1000. FCM: 1µg for 10^6 cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.