Integrin alpha 3 antibody

Catalogue Number: GTX82120-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:117
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:integrin subunit alpha 3 , CD49C , FRP-2 , GAP-B3 , GAPB3 , ILNEB , MSK18 , VCA-2 , VL3A , VLA3a
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Immunogen Sequence: GI # 4504747, sequence 1015-1051 Recombinant integrin α 3 isoform a
Application: WB

Description

Description: Integrin alpha-3/beta-1 is a receptor for fibronectin. laminin. collagen. epiligrin. thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 encodes the integrin alpha 3 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 ('VLA-3'). very common antigen 2 ('VCA-2'). extracellular matrix receptor 1 ('ECMR1'). and galactoprotein b3 ('GAPB3').

Additional Text

Gene Name

ITGA3

Uniprot ID

P26006

Gene ID

3675

Purification

Affinity Purified

Molecular Weight

117

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.