PTPRF antibody
Catalogue Number: GTX82141-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 213 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | protein tyrosine phosphatase receptor type F , BNAH2 , LAR |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Chicken |
| Clone: | |
| Isotype: | IgY |
| Immunogen: | Immunogen Sequence: GI # 4506311, sequence 1151-1225 Recombinant protein tyrosine phosphatase, receptor type, F isoform 1 |
| Application: | WB |
Description
Description: Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth. differentiation. mitotic cycle. and oncogenic transformation. This PTP possesses an extracellular region. a single transmembrane region. and two tandem intracytoplasmic catalytic domains. and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains. and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions. as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese. insulin-resistant individuals. and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene. which encode distinct proteins. have been reported.
Additional Text
Uniprot ID
P10586
Gene Name
PTPRF
Purification
Affinity Purified
Gene ID
5792
Molecular Weight
213
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX82141 Datasheet
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