CARD14 antibody
Catalogue Number: GTX82208-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 113 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | caspase recruitment domain family member 14 , BIMP2 , CARMA2 , PRP , PSORS2 , PSS1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Chicken |
| Clone: | |
| Isotype: | IgY |
| Immunogen: | Immunogen Sequence: GI # 16507955, sequence 221-330 Recombinant caspase recruitment domain protein 14 isoform 2 |
| Application: | WB |
Description
Description: Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family. a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family. which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10. a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells. this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.
Additional Text
Gene Name
CARD14
Gene ID
79092
Uniprot ID
Q9BXL6
Purification
Affinity Purified
Molecular Weight
113
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX82208 Datasheet
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