Stanniocalcin 2 antibody

Catalogue Number: GTX82231-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:33
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:stanniocalcin 2 , STC-2 , STCRP
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Immunogen Sequence: GI # 4507267, sequence 20-302 Recombinant stanniocalcin 2
Application: WB

Description

Description: Has an anti-hypocalcemic action on calcium and phosphate homeostasis. This protein is a secreted. homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport. cell metabolism. or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction. reduced bone and skeletal muscle growth. and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

Additional Text

Gene Name

STC2

Uniprot ID

O76061

Gene ID

8614

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

33

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.