PRX III antibody

Catalogue Number: GTX82299-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:28
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:peroxiredoxin 3 , AOP-1 , AOP1 , HBC189 , MER5 , PRO1748 , SP-22 , prx-III
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Immunogen Sequence: GI # 5802974, sequence 1-256 Recombinant peroxiredoxin 3 isoform a
Application: WB

Description

Description: Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. This protein is a protein with antioxidant function and is localized in the mitochondrion. This protein shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved. and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation. differentiation. and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

Additional Text

Gene Name

PRDX3

Uniprot ID

P30048

Gene ID

10935

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

28

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.