GSK3 beta antibody

Catalogue Number: GTX82427-GTX

Manufacturer:	GeneTex
Preservative:	0.02% Sodium azide\|0.02% Sodium azide
Molecular Weight:	47
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	glycogen synthase kinase 3 beta
Shipping Condition:	Blue Ice
Unit(s):	50 ug
Host name:	Chicken
Clone:
Isotype:	IgY
Immunogen:	Immunogen Sequence: GI # 21361340, sequence 21-36 Synthetic peptide sequence of glycogen synthase kinase 3β.
Application:	ELISA, WB

Overview
Datasheets

Description

Description: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase. MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain. thereby reducing its affinity for DNA. Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms. alpha (GSK3A; MIM 606784) and beta. show a high degree of amino acid homology (Stambolic and Woodgett. 1994). GSK3B is involved in energy metabolism. neuronal cell development. and body pattern formation (Plyte et al.. 1992).[supplied by OMIM].

Additional Text

Gene ID

2932

Gene Name

GSK3B

Uniprot ID

P49841

Purification

Affinity Purified

Molecular Weight

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX82427 Datasheet

Price

£506.00

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