NF-L antibody

Catalogue Number: GTX82644-GTX

Manufacturer:GeneTex
Preservative:10 mM Sodium azide
Molecular Weight:62
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:neurofilament light , CMT1F , CMT2E , CMTDIG , NF-L , NF68 , NFL , PPP1R110
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Preparation of bovine spinal cord NF-L
Application: WB, IHC

Description

Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]

Additional Text

Gene Name

NEFL

Gene ID

4747

Uniprot ID

P07196

Molecular Weight

62

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

Optimal working dilutions should be determined experimentally by the end user.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.