Catalogue Number: GTX82959-GTX
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 12 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 7 ml |
| Host name: | Guinea Pig |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Purified human insulin conjugated to carrier protein |
| Application: | IHC-P |
Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
INS
3630
P01308
Purified
Polyclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
For IHC-P: Supplied in ready to use form. Optimal dilutions/concentrations should be determined by the end user.
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.