Insulin antibody (Ready-to-use)

Catalogue Number: GTX82959-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:12
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10
Shipping Condition:Blue Ice
Unit(s): 7 ml
Host name: Guinea Pig
Clone:
Isotype: IgG
Immunogen: Purified human insulin conjugated to carrier protein
Application: IHC-P

Description

Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Additional Text

Gene Name

INS

Gene ID

3630

Uniprot ID

P01308

Purification

Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

For IHC-P: Supplied in ready to use form. Optimal dilutions/concentrations should be determined by the end user.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.