SIRT7 antibody
Catalogue Number: GTX85103-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 45 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | sirtuin 7 , SIR2L7 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Chicken |
| Clone: | |
| Isotype: | IgY |
| Immunogen: | SIRT7 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human SIRT7.The immunogen is located within amino acids 50 - 100 of SIRT7. |
| Application: | ELISA, WB |
Description
Description: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT7 is a nucleolar protein that positively regulates RNA polymerase I transcription and has been postulated to enable cells to sustain critical functions by inhibiting cell growth under severe stress conditions.
Additional Text
Gene Name
SIRT7
Uniprot ID
Q9NRC8
Purification
Affinity Purified
Gene ID
51547
Molecular Weight
45
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Application Notes
WB: 0.5 - 1 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX85103 Datasheet
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